While at school, Taniyama Mai and her friends like to exchange ghost stories. Apparently, there is an abandoned school building on their campus that is the center of many ghost stories. During the story, they are interrupted by a mysterious male figure. The person turns out to be Shibuya Kazuya, a 17-year-old who is president of the Shibuya Psychic Research Company. He was called by the principal to investigate the stories surrounding the abandoned school building. The next day, on the way to school, Mai passes the school building in question. While examining a strange camera she spotted inside, she gets surprised by Kazuya's assistant. Unknowingly interfering with the investigation, Mai breaks the camera and Kazuya's assistant gets injured. Kazuya forcefully hires Mai in order to pay for the camera and replace his injured assistant. From that point on, Mai begins to learn about the paranormal world and the profession of ghost hunting. [Written by MAL Rewrite]

Ritsuka Tachibana has always been a good student, so she is completely shocked when she is suddenly summoned by the student council. Even more, they seem to think of Ritsuka as a troublemaker. Led by the handsome Rem Kaginuki, the student council—also consisting of Urie Sogami, Shiki Natsumizaka and Mage Nanashiro—tries to question her, but it soon becomes clear that they have ulterior motives. However, this is only the beginning. When her mother gets kidnapped, her life is turned upside down, and Ritsuka gets drawn into a world of vampires and devils. Both groups are searching for the "Grimoire," a forbidden item allowing its owner to rule the world. The return of her brother Lindo from overseas gives her hope, but even he appears to be hiding something. In a world filled with secrets, Ritsuka questions whom she can trust in this dark musical tale, while the handsome and dangerous members of the student council compete for her attention. [Written by MAL Rewrite]

In desperation, Edward Elric sacrificed his body and soul to rescue his brother Alphonse, and is now displaced in the heart of Munich, Germany. He struggles to adapt to a world completely foreign to him in the wake of the economic crisis that followed the end of World War I. Isolated and unable to return home with his alchemy skills, Edward continues to research other methods of escaping the prison alongside colleagues who bear striking resemblances to many of the people he left behind. As dissent brews among the German citizenry, its neighbors also feel the unrest of the humiliated nation. Meanwhile, Alphonse continues to investigate Edward's disappearance, delving into the science of alchemy in the hopes of finally reuniting with his older brother. [Written by MAL Rewrite]

The second season of Strike the Blood which adapts three arcs from the 9th, 11th, and 12th light novel volumes.