Third season of .

Ten years after the Bubble War, the dichotomy between the rich and the poor in the world becomes more prominent and Japan is no exception. The rich seek to satisfy their desires and derive pleasure for themselves, and Tokyo has materialized into such a city as a result. Saiga, once a war photographer, works for Hibara Ginza in the capitalist state of Tokyo. He infiltrates the Roppongi Club, a secretive base located in the red light district of the city, to collect information about them. However, he was caught in the process and brought forward to a girl called Kagura who was in the midst of a ritual. His contact with Kagura awakens his special ability: the power to make things explode when photographed. In order to unravel the mystery behind the Roppongi Club and Kagura, Saiga begins his solitary battle.

Ichigo Momomiya is excited to start high school and fall in love. She is in luck when she meets the popular and good-looking Masaya Aoyama, and she immediately develops a crush on him. When Ichigo learns that Aoyama is passionate about the environment, she seizes the chance to ask him out thanks to some tickets to an exhibition about endangered animals. During their date, Ichigo is struck by a mysterious light and faints. Waking up to the sight of Aoyama, she remains unharmed—but they both must escape from a giant rat-like creature after it injures Aoyama. To save her crush, Ichigo awakens her powers and transforms into a heroine with the skills of a cat. After she defeats the monster, researchers Ryou Shirogane and Keiichiro Akasaka explain that Ichigo was chosen to become a part of the Mew Project: a group of five magical girls whose DNA has been infused with those of certain endangered species. Now, Ichigo must find the rest of her teammates to defeat the Chimera Anima—beings infected by aliens who want to take over the world—before it is too late.

In Stern Bild City, those with special abilities are called "NEXT," and can use their powers for good or bad. A unique organized group of NEXT appear regularly on Hero TV, where they chase down evildoers to bring limelight to their sponsors and earn Hero Points in the hopes of becoming the next "King of Heroes." Kotetsu T. Kaburagi, known as "Wild Tiger," is a veteran hero whose performance has been dwindling as of late, partially due to his inability to cooperate with other heroes. After a disappointing season in which most of the other heroes far outperformed Tiger, he is paired up with a brand new hero who identifies himself by his real name—Barnaby Brooks Jr. Barnaby, nicknamed "Bunny" by his frivolous new partner, quickly makes it clear that the two could not be more different. Though they mix as well as oil and water, Tiger and Bunny must learn to work together, both for the sake of their careers and to face the looming threats within Stern Bild. [Written by MAL Rewrite]